![]() Some drugs that treat high blood pressure, such as Procardia and Adalat CC (both nifedipine).Some statin drugs to lower cholesterol, such as Zocor (simvastatin) and Lipitor (atorvastatin). ![]() Here are examples of some types of drugs that grapefruit juice can cause problems (interact) with: Food and Drug Administration has required that some prescription and over-the-counter (OTC) drugs generally taken by mouth include warnings against drinking grapefruit juice or eating grapefruit while taking the drug. Grapefruit juice and grapefruit can affect the way your medicines work, and that food and drug interaction can be a concern. Grapefruit has vitamin C and potassium, nutrients your body needs to work properly. ![]() Department of Agriculture.Grapefruit juice and grapefruit can be part of a healthy diet. This research was published in the Journal of Applied Microbiology and Biotechnology and theJournal of Agricultural and Food Chemistry.ĪRS is the principal intramural scientific research agency in the U.S. That provides researchers with evidence that fungal proteins could be responsible for removing the FCs from the grapefruit juice. In studies, they found that edible mushrooms such as morels, oyster and button mushrooms-when dried, pulverized and added to grapefruit juice-also removed FCs. Myung and his team decided to also test edible fungi, or mushrooms. niger is one of the most common species of the genus Aspergillus that can cause black mold on certain fruits and vegetables but often doesn’t cause human disease. Enzymatic inactivation of these compounds may be a means of eliminating them from commercial grapefruit juice, and work to identify these enzymes in A. niger either bound these FCs or enzymatically broke them down into other products. ![]() Grapefruit juice contains three main FCs. The grapefruit industry may have lost customers who no longer drink grapefruit juice due to their medications.ĪRS chemists Kyung Myung and John Manthey and microbiologist Jan Narciso at the ARS Citrus and Subtropical Products Laboratory in Winter Haven, Fla., began the study using a fungus-Aspergillus niger-to bind and break down FCs in grapefruit juice. Grapefruit juice can interfere with the metabolism of certain medications used to treat a wide range of conditions such as allergies, abnormal heart rhythm, depression, hypertension, infections, heart disease, and high cholesterol. Two well-known phytochemicals are Vitamins C and E. FCs are phytochemicals commonly found in plants. Grapefruit contains furanocomarins (FCs), which inhibit the enzymatic activity responsible for metabolizing certain prescribed medications and allowing more of the medication to enter the bloodstream. Citrus peel waste a potential source of ethanolįungi May Hold Key to Reducing Grapefruit Juice Interactions with MedicationsĪ fungus may help solve a problem of a grapefruit compound that interacts negatively with certain prescription drugs, according to studies by Agricultural Research Service (ARS) scientists.U.S.-Thai scientific efforts peg guava's nutritional value.Photo courtesy of Florida Department of Citrus. ARS scientists have found that certain fungi can prevent compounds in grapefruits from interfering with some prescription medicines.
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